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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fff6279dc6248a575d8cca6d515f3db9b8ca2bbff038c9b90eadbae477c418a' 
  AND token = 'EYhgwVyT/BHtA2Fs4t3/utMvHzAW6l5athBcQ2w0c1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}