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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e765256b3616ceec9f5660a6c8c0ff5c819b0358b995340568dd9e0c2d3fa73' 
  AND token = 'CIw8Y3XSP5q3oj42oNb5o6cOYbb5cHqSpaw+GnzGeYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}