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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfae8ca722d5f81c0d71f138f00f93003037083e69b8776561a867484bc562df' 
  AND token = 'A1sAv8RO/K47ctsYvQaheiAQTXqKHheq2nJMB13PFJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}