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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2246d53a57607ec6180768d8ea94aea4a833d5c04c999bb23a9e05cd6c62a6df' 
  AND token = 'BGzNS+O0WaBv/LMsVTpH9nP1uvsTMXUDrZBnyaGULWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}