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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e609ab08f7f29772b6b51dc732c3f4a555081a1e5f7786e28b9968288e7e4ae' 
  AND token = 'eUARsElygOtE1PBn0Bgd2cWpvYB2SLXsPBlUr0Y0DQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}