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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e81fabf1435a70d354c851bdb0e45d14b76666d95a40b03d3e101e36deb60eb' 
  AND token = 'raoCOI4YlfEPB/SQqfuHp9w/YTFhkcIbglCL2FEACoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}