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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a222c0adc31d9edba0d4904e50e28573fa0d3e9dc9311169a819872790bad71b' 
  AND token = 'FRfN8Oxg8Ysl/odKO1C4dRd7avHU33YFRvODBXhKzBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}