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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f8acf9d42ad4f41cfff18f13f8d58fd521c2e3ca4abd5a21246701ec5ee4d0b' 
  AND token = 'QEWD+m/aIfR/fD8orTgMaSSvrqZpi9MyjccxRz45wVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}