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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1000826d7ef162d634752c58a864a78a1fc6e1e49cf0086fadbb8d8ce638500f' 
  AND token = 'RHUa3b92zWRTjQQ0GN5CeKwgIEjhO+M4ZRVh0c1grEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}