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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '177feeaca60e232ac1c6302fd5d7603099a5f53988bf75b60e1437c385d53be1' 
  AND token = 'fub+eSM6vzquXyxg3anv39xcq7kBP52BzsMNFuFh474=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}