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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51b2e984e64eb538d1b22a46af89de7de7268c25252a0934205116936d8cdf24' 
  AND token = 'GaPpRtqLMyZund7T6fb9qIcF2tEMxtg6nCrj3gNvoH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}