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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d99fbced3b2b9cc89676fa7c814aa791616d317ab9d2515a8e6ce2a233923cf' 
  AND token = 'ThQXNi1+WiAd/lqN7yAje7I7cOQPmIYRqJa7tw/zcR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}