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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6f3cdafd8f19b0204204fa7c7af0f45e25b3c527e4d9d995c572844b840480' 
  AND token = 'FM6Ovn7Y7/kuWxnmzPEvSF1h0XJ77dLLltemI6vFs7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}