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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cb74525b31fa210710b568bbcc0d5eee1fa668691ba8f5757e90b3f9c7e5388' 
  AND token = 'Vi6F85xiYZV4ZsYNfAnbKGxBNWGwsla+7F+Efuotpq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}