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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d04edb0ab6546ce89e995e76df456988a5ce373dfa5e90686e28ada3cf9d65d' 
  AND token = 'rpYHCDEoWb2Mibqu42UK2qSU/IqyY2dD4xrciy2dpiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}