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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbb10955f3bd0eb035c22482c77e42e451bb390e10e2c05f256c91c9afe42e39' 
  AND token = 'xhKEvP/M4GegOVB+yfpFeLLVDmvQGbwO2CfyCQaPxHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}