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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f529651fc24cce96c69e64c7c042dc00c6790c555466a953eafbf8079a4b63e3' 
  AND token = 'PuqhAfJGoXaTsQ7qv4sfTMbSU/8OKYgxKTNBEGwETu8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}