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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9a8f537f0b126c696aa77522a2fa5f168e97f16714de157c2f215fda4885e5' 
  AND token = 'DI+96xxFsSlLnaqeP8IMKkiJoUGDSd/10bBxInoGAEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}