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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4648b78821c4909c42cd83bbdec90e0562654331918ce03f8a464e8b1c710a4b' 
  AND token = 'Doimv/wqe3csgfT+Lnxe4At2hKICnYbneQCkJP0bsXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}