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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9c57c04190d3f00d0e6c83e736642cc107cd957f71c8f94681cda7007f9e56' 
  AND token = 'J3KY2Q4iGeOecBXaDRxPQwgnERMHi/ZYB6PMS4tp4d0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}