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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2862370f540733cf99176d9beb3d5d9e4847ab285759828c8e517555254d6c6' 
  AND token = 'HmKGeQvyI3M1WuJ3LeGMwH+oMdQ/BSArUWgWvEuM5Ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}