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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d53d07febff21364591f3016260b1fc9f927e048f29ac56b209c5df8b99347e' 
  AND token = '4qP32yKDaoYjnny/1fcY/IGTGGkAHrNor8JCWB8pjgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}