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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '92a40ef2e6cc46f5fd4ac0b49996ade1fd04f728c7a7d59e2af72270a8ce294e' 
  AND token = 'mEw368d8WfndPFp/bdh95Sk3iF5d8HFefNVjyHNjc5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}