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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66288170d168dc22565b76888af726ababe454d55d319d2ac878a9521b0e9a95' 
  AND token = 'iM1o/WOLwhEH9iZp/mBCollDkLomNKT1nfi/kmB90G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}