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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cb66c80f8b0e74341637ea25a51e0daa9720f82e7f3eceaefa1d564037202a3' 
  AND token = 'PC3NVQiqN9gtP0u0GSircN5ofKoS5OV8qx+nOzbBK1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}