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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7640b9b323e7fbef23fb5d71bd349fc7a92c085ae09fac0af1bc9b96384cc574' 
  AND token = 'TYZ3PEKx1GP6dqT9YAoNO171b/W8nYGL/XTG7p+0dGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}