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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d2f56a5adca7f29ac318aefb2c67efa949b58e8337d6268ecc9e38745499d7' 
  AND token = 'DDJm5ZeUURWs2HuoZ9AsXmGE3fJUHN7K4xNaRRK6sxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00072

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}