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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7d39c777c9863fc69b4c6f6649b49c9c10ea6fb51b143340f463f4f870aac4c' 
  AND token = 'Vr3Z66yMZml4dBX0FixuQ4p5NMTkfmMte8eqMy6mEcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}