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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73250c2dca8345ee15c47b8bb357c78f73b49984dc3468bf18b90ea07fa61069' 
  AND token = 'hjZ/UI0CuTfE/4v47BC5OacjwU5MpJ4fIwNKJbiBdoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}