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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2921fead722921bb4d3110afafa37ba884d8a709e8a91c6139a4f55985401d9' 
  AND token = 'EREvRrp+Q3TPb5iAysT+iG3GrcpVK7jHhG0xbGr6lZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}