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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fac5146e22446d1f15f6e30acffb44175d1f5d9784212be0e39410e3f2da5a41' 
  AND token = 'FW/3CCGuAOX01soZ+LA5TmHHQRymlxWjH4vTExlZCM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}