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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cca096d301bd1883327f8135a460c99b550a99021cc6ae9ba9a9e3b961f24c1' 
  AND token = '5Uwzs47hjCbmPcQBc8G5sR+1o601PQODfJloMF83XYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}