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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae05531f8361845362411bf24b362e72bf344b7f8c770e30aa59398b0d20603' 
  AND token = 'Jaa9I0i9TxSavb0kcByFueoj/PSy4A04NflXycnvEXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}