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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2337a81c0a18468fee9e27f4d5a74a63da9886074a0842f56bbf681bb96f7ad' 
  AND token = 'Df23ibg5itV7H4UN1277eQR9jTIQZmrwU15H9vs4BzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}