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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63c764863542aa34e546aecc0e3d7b2a4e3ae00afbfc0d58f11648a98e10e374' 
  AND token = 'ROFMK7MEV/3lN4Pfcn8DloaBgtOVCs3KT7Y9znZpsWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}