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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '174d3dee3a952eb08e8f2a63df9ef739cc349adb7d3f76e4473b99a364dd1405' 
  AND token = 'wMe0D6qfp95jXm9wE0uSe3jadYbikHEU8P+WboBNPqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}