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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50dc7eb94db76e1e3e0a118a76f8cf96908f721faa0a4817d54c58e74b417bc' 
  AND token = '1jQ1uah9VXTtPQxr9wkZN04+1YOjQ60cTIF/1TjbSD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}