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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f747d7b452810a816364f1601318b267475a2815ad003ca2c58444f8824caa' 
  AND token = '7JWIzJiP5iknjrWFtTzP31N5JOIEikgKhRDQo7aQ3BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}