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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '262e79ff2206b0df881e5eee00bb4fdc1050c7bac2f96a5708d0461ecc0b4669' 
  AND token = 'pYQ7awZctdGAmg7VD3F+/rdqxktjH4ThBCDdcfQIdQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}