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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5ddb25cf7e26eefc9dca2ddae5a5fe9019086f3e14b599fa2f728045f5e4d29' 
  AND token = 'sA+UAsGDi51ym8pa7/IES/tpjGFUqiH1ZQd524UAH70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}