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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5efb5f9604cb690cfb3ab2f9294592ff3047886f598af47e13c412f8c353d81b' 
  AND token = 'CmeM8BN0fB4t4YQH5rvQGWWsORVKeAazKhy84iGZHzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}