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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b4f425121d2879019208f91f02d87a2cc830fb9438f274719086f15ca03da7b' 
  AND token = 'LhtJikRIE8ixs05QlFscG4/4qb4H4pmGj3LTc6xX27Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}