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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b95b853bd3f25031fd9ba4b68cf788fab25d097959d6d749663ddbd854d58522' 
  AND token = 'mTV5axq9uQk2ejAFm/I1MSLK7pzVvN1Km81tG5iwWUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}