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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3eee71f46590d0a62f148b05ce3c2a9190567be35c8df6d0622f9224dae22a80' 
  AND token = 'PZITy+a3pIyuiCDHtk7dx/+4FEGRFsizjXoLW31JGMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}