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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3c642e1471b43380842ef37d5a2911203015fc10cc6eeeec19e09c36281cdd2' 
  AND token = 'Ygot88fsclYH/gzYcd5y+Ew2dZyD2q1mEYE6Gd6aJlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}