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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4b5a4bb826781eed2df9d7e8a4e48eabd8e649c5e8c3eb9c959514e3e1227a' 
  AND token = '0xS1KOH/Erl+NuCxT/LDzDOONKv/5CSjRRcJmGO9hAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}