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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6dfcb09f1d353c42c60ccaf264c76a4c524242a5ec8e404a1c3134bb383b4f4' 
  AND token = '+WKxnXaMFrJRZ9Pp3VvaP9IfBJIYyslMxa9f73kDHrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00151

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}