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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f2a724721733022efec6bbb4a1f3aee3e37281bfa78cd365e0be5da12e0e2a6' 
  AND token = '6X5seTO+VI2d/VZ/2/SsimpkNhC2tOpv6TrvBG1qnto=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}