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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b286ca39c5703419cdaecea0b35bf60a8d2bb1ab78f9f734e2d600e7b21dec3f' 
  AND token = '3fsmG8ag6uhyYBclXXZ2XXOc/Wd4HF2MW9rmXuE70Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}