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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153dc1d2688ee613d860cdb884aa5637bccc30a4ce4d40ebb8985c8b0cee672d' 
  AND token = 'MahmGbzuIUzAHaY4/EZu8gdVvgQ9NU9oY3D6OTllkaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}